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limk1 2 inhibitor limki3  (Tocris)


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    Structured Review

    Tocris limk1 2 inhibitor limki3
    Cofilin is involved in cyclosporine A (CsA)‐induced actin reorganization through its phosphorylation site. A, Fluorescence images of Lilly Laboratories Porcine Kidney‐1 actin cytoskeleton labeled with TRITC‐Phalloidin. Scale bar 10 µm. B, Quantification of red fluorescence‐positive area. Mean ± SEM. One‐way ANOVA plus Tukey's post‐test (* P < .05, *** P < .001) (n = 4). Drug condition: (a) Vehicle (b) 100 µg/mL S3R (c) 10 µmol/L <t>LIMKi3</t> (d) 5 µmol/L CsA (e) S3R + CsA (f) LIMKi3 + CsA. Exposure time: 24 h (n = 4)
    Limk1 2 Inhibitor Limki3, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 27 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/limk1 2 inhibitor limki3/product/Tocris
    Average 93 stars, based on 27 article reviews
    limk1 2 inhibitor limki3 - by Bioz Stars, 2026-02
    93/100 stars

    Images

    1) Product Images from "Cyclosporine A inhibits MRTF‐SRF signaling through Na + /K + ATPase inhibition and actin remodeling"

    Article Title: Cyclosporine A inhibits MRTF‐SRF signaling through Na + /K + ATPase inhibition and actin remodeling

    Journal: FASEB bioAdvances

    doi: 10.1096/fba.2019-00027

    Cofilin is involved in cyclosporine A (CsA)‐induced actin reorganization through its phosphorylation site. A, Fluorescence images of Lilly Laboratories Porcine Kidney‐1 actin cytoskeleton labeled with TRITC‐Phalloidin. Scale bar 10 µm. B, Quantification of red fluorescence‐positive area. Mean ± SEM. One‐way ANOVA plus Tukey's post‐test (* P < .05, *** P < .001) (n = 4). Drug condition: (a) Vehicle (b) 100 µg/mL S3R (c) 10 µmol/L LIMKi3 (d) 5 µmol/L CsA (e) S3R + CsA (f) LIMKi3 + CsA. Exposure time: 24 h (n = 4)
    Figure Legend Snippet: Cofilin is involved in cyclosporine A (CsA)‐induced actin reorganization through its phosphorylation site. A, Fluorescence images of Lilly Laboratories Porcine Kidney‐1 actin cytoskeleton labeled with TRITC‐Phalloidin. Scale bar 10 µm. B, Quantification of red fluorescence‐positive area. Mean ± SEM. One‐way ANOVA plus Tukey's post‐test (* P < .05, *** P < .001) (n = 4). Drug condition: (a) Vehicle (b) 100 µg/mL S3R (c) 10 µmol/L LIMKi3 (d) 5 µmol/L CsA (e) S3R + CsA (f) LIMKi3 + CsA. Exposure time: 24 h (n = 4)

    Techniques Used: Phospho-proteomics, Fluorescence, Labeling

    Cofilin is involved in cyclosporine A (CsA)‐induced inhibition of myocardin‐related transcription factors‐serum response factor (SRF) transcription activity. SRF transcription activity was measured by luciferase gene reporter assay in Lilly Laboratories Porcine Kidney‐1 SRE exposed 24 h to: (A) S3‐R 100 µg/mL; S3R + CsA. (n = 6); (B) LIMKi3 10 µmol/L; LIMKi3 + CsA. (n = 7). Mean ± SEM. One‐sample t test for vs control comparison, One‐way ANOVA plus Tukey's post‐test for multiple condition comparison (* P < .01, *** P < .001)
    Figure Legend Snippet: Cofilin is involved in cyclosporine A (CsA)‐induced inhibition of myocardin‐related transcription factors‐serum response factor (SRF) transcription activity. SRF transcription activity was measured by luciferase gene reporter assay in Lilly Laboratories Porcine Kidney‐1 SRE exposed 24 h to: (A) S3‐R 100 µg/mL; S3R + CsA. (n = 6); (B) LIMKi3 10 µmol/L; LIMKi3 + CsA. (n = 7). Mean ± SEM. One‐sample t test for vs control comparison, One‐way ANOVA plus Tukey's post‐test for multiple condition comparison (* P < .01, *** P < .001)

    Techniques Used: Inhibition, Activity Assay, Luciferase, Reporter Assay, Control, Comparison



    Similar Products

    limk1 2 inhibitor limki3  (Tocris)
    93
    Tocris limk1 2 inhibitor limki3
    Cofilin is involved in cyclosporine A (CsA)‐induced actin reorganization through its phosphorylation site. A, Fluorescence images of Lilly Laboratories Porcine Kidney‐1 actin cytoskeleton labeled with TRITC‐Phalloidin. Scale bar 10 µm. B, Quantification of red fluorescence‐positive area. Mean ± SEM. One‐way ANOVA plus Tukey's post‐test (* P < .05, *** P < .001) (n = 4). Drug condition: (a) Vehicle (b) 100 µg/mL S3R (c) 10 µmol/L <t>LIMKi3</t> (d) 5 µmol/L CsA (e) S3R + CsA (f) LIMKi3 + CsA. Exposure time: 24 h (n = 4)
    Limk1 2 Inhibitor Limki3, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/limk1 2 inhibitor limki3/product/Tocris
    Average 93 stars, based on 1 article reviews
    limk1 2 inhibitor limki3 - by Bioz Stars, 2026-02
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Cofilin is involved in cyclosporine A (CsA)‐induced actin reorganization through its phosphorylation site. A, Fluorescence images of Lilly Laboratories Porcine Kidney‐1 actin cytoskeleton labeled with TRITC‐Phalloidin. Scale bar 10 µm. B, Quantification of red fluorescence‐positive area. Mean ± SEM. One‐way ANOVA plus Tukey's post‐test (* P < .05, *** P < .001) (n = 4). Drug condition: (a) Vehicle (b) 100 µg/mL S3R (c) 10 µmol/L LIMKi3 (d) 5 µmol/L CsA (e) S3R + CsA (f) LIMKi3 + CsA. Exposure time: 24 h (n = 4)

    Journal: FASEB bioAdvances

    Article Title: Cyclosporine A inhibits MRTF‐SRF signaling through Na + /K + ATPase inhibition and actin remodeling

    doi: 10.1096/fba.2019-00027

    Figure Lengend Snippet: Cofilin is involved in cyclosporine A (CsA)‐induced actin reorganization through its phosphorylation site. A, Fluorescence images of Lilly Laboratories Porcine Kidney‐1 actin cytoskeleton labeled with TRITC‐Phalloidin. Scale bar 10 µm. B, Quantification of red fluorescence‐positive area. Mean ± SEM. One‐way ANOVA plus Tukey's post‐test (* P < .05, *** P < .001) (n = 4). Drug condition: (a) Vehicle (b) 100 µg/mL S3R (c) 10 µmol/L LIMKi3 (d) 5 µmol/L CsA (e) S3R + CsA (f) LIMKi3 + CsA. Exposure time: 24 h (n = 4)

    Article Snippet: LIMK1/2 inhibitor LIMKi3 (#4745) was provided by Tocris.

    Techniques: Phospho-proteomics, Fluorescence, Labeling

    Cofilin is involved in cyclosporine A (CsA)‐induced inhibition of myocardin‐related transcription factors‐serum response factor (SRF) transcription activity. SRF transcription activity was measured by luciferase gene reporter assay in Lilly Laboratories Porcine Kidney‐1 SRE exposed 24 h to: (A) S3‐R 100 µg/mL; S3R + CsA. (n = 6); (B) LIMKi3 10 µmol/L; LIMKi3 + CsA. (n = 7). Mean ± SEM. One‐sample t test for vs control comparison, One‐way ANOVA plus Tukey's post‐test for multiple condition comparison (* P < .01, *** P < .001)

    Journal: FASEB bioAdvances

    Article Title: Cyclosporine A inhibits MRTF‐SRF signaling through Na + /K + ATPase inhibition and actin remodeling

    doi: 10.1096/fba.2019-00027

    Figure Lengend Snippet: Cofilin is involved in cyclosporine A (CsA)‐induced inhibition of myocardin‐related transcription factors‐serum response factor (SRF) transcription activity. SRF transcription activity was measured by luciferase gene reporter assay in Lilly Laboratories Porcine Kidney‐1 SRE exposed 24 h to: (A) S3‐R 100 µg/mL; S3R + CsA. (n = 6); (B) LIMKi3 10 µmol/L; LIMKi3 + CsA. (n = 7). Mean ± SEM. One‐sample t test for vs control comparison, One‐way ANOVA plus Tukey's post‐test for multiple condition comparison (* P < .01, *** P < .001)

    Article Snippet: LIMK1/2 inhibitor LIMKi3 (#4745) was provided by Tocris.

    Techniques: Inhibition, Activity Assay, Luciferase, Reporter Assay, Control, Comparison